任深圳，男，汉，1992.10，中共党员，博士，讲师，硕士生导师，校元光学者

【工作与教育经历】

2020.10-今 永利官网，3044am永利，讲师，硕士生导师

2015.09-2020.06 南京大学，生命科学学院，博士

【研究领域】

1）多功能纳米载体在肿瘤多模态成像、光学治疗、免疫治疗及联合治疗等方面的应用；

2）靶向小分子抑制剂的设计、合成及生物活性研究。

【研究生招生学科方向】

硕士：生物学、化学

【教研/科研项目】

1）河北省高等学校科学技术研究项目重点项目，2021.01-2023.12，10万，主持；

2）国家自然科学基金面上项目，21877060，2019.01-2022.12，67.5万元，参与；

3）国家自然科学基金面上项目，81671390，2017.01-2020.12，60万元，参与。

【代表性论文】

[1] Dan Zhu; Bin Wang; Xiao-Hua Zhu; Hai-Liang Zhu*; Shen-Zhen Ren*; A MnO₂-coated multivariate porphyrinic metal-organic framework for oxygen self-sufficient chemo-photodynamic synergistic therapy,  Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 37: 102440.

[2] Shen-Zhen Ren; Xiao-Hua Zhu; Bin Wang; Ming Liu; Shu-Kai Li; Yu-Shun Yang*; Hai-Long An*; Hai-Liang Zhu*, A Versatile Nanoplatform based on Multivariate Porphyrinic Metal-Organic Frameworks for Catalytic Cascade-Enhanced Photodynamic Therapy,  Journal of Materials Chemistry B , 2021, 9(23): 4678-4689.

[3] Shen-Zhen Ren; Bin Wang; Xiao-Hua Zhu; Dan Zhu; Ming Liu; Shu-Kai Li; Yu-Shun Yang*; Zhong-Chang Wang*; Hai-Liang Zhu*, Oxygen Self-Sufficient Core-Shell Metal-Organic Framework-based Smart Nanoplatform for Enhanced Synergistic Chemotherapy and Photodynamic Therapy,  ACS Applied Materials & Interfaces , 2020, 12(22): 24662-24674.

[4] Xiao-Hua Zhu; Jun-Xi Du; Dan Zhu; Shen-Zhen Ren*; Kun Chen*; Hai-Liang Zhu*; Recent Research on Methods to Improve Tumor Hypoxia Environment, 2020, 2020: 5721258.

[5] Shen-Zhen Ren; Dan Zhu; Xiao-Hua Zhu; Bin Wang; Yu-Shun Yang; Wen-Xue Sun; Xiao-Ming Wang; Peng-Cheng Lv*; Zhong-Chang Wang*; Hai-Liang Zhu*, Nanoscale Metal-Organic Frameworks Coated by Biodegradable Organosilica for pH and Redox Dual Responsive Drug Release and High-Performance Anticancer Therapy,  ACS Applied Materials & Interfaces , 2019, 11(23): 20678-20688.

[6] Shen-Zhen Ren^#; Zhong-Chang Wang^#*; Dan Zhu; Xiao-Hua Zhu; Fa-Qian Shen; Song-Yu Wu; Jin-Jin Chen; Chen Xu*; Hai-Liang Zhu*, Design, Synthesis and Biological Evaluation of Novel Ferrocene-Pyrazole Derivatives Containing Nitric Oxide Donors as COX-2 Inhibitors for Cancer Therapy,  European Journal of Medicinal Chemistry, 2018, 157: 909-924.

[7] Shen-Zhen Ren^#; Zhong-Chang Wang^#*; Xiao-Hua Zhu; Dan Zhu; Zhang Li; Fa-Qian Shen; Yong-Tao Duan; Han Cao; Jing Zhao*; Hai-Liang Zhu*, Design and Biological Evaluation of Novel Hybrids of 1, 5-Diarylpyrazole and Chrysin for Selective COX-2 Inhibition,  Bioorganic & Medicinal Chemistry , 2018, 26(14): 4264-4275.

[8] Juan Sun^#; Shen-Zhen Ren^#; Xiao-Yuan Lu; Jing-Jing Li; Fa-Qian Shen; Chen Xu*; Hai-Liang Zhu*, Discovery of A Series of 1, 3, 4-Oxadiazole-2 (3H)-thione Derivatives Containing Piperazine Skeleton as Potential FAK Inhibitors,  Bioorganic & Medicinal Chemistry , 2017, 25(9): 2593-2600.

[9] Qi Liu; Wei-Kang Shi; Shen-Zhen Ren; Wei-Wei N; Wei-Yi Li.; Hui-Min Chen; Pei Liu; Jing Yuan; Xiao-Su He; Jia-Jia Liu; Peng Cao; Pu-Zhen Yang; Zhu-Ping Xiao*; Hai-Liang Zhu*, Arylamino Containing Hydroxamic Acids as Potent Urease Inhibitors for the Treatment of Helicobacter Pylori Infection,  European Journal of Medicinal Chemistry, 2018, 156: 126-136.

[10] Wei-Wei Ni; Qi Liu; Shen-Zhen Ren; Wei-Yi Li; Li-Li Yi; Heng Jing; Li-Xin Sheng; Qin Wan; Ping-Fu Zhong; Hai-Lian Fang; Hui Ouyang; Zhu-Ping Xiao*; Hai-Liang Zhu*, The synthesis and evaluation of phenoxyacylhydroxamic acids as potential agents for Helicobacter pylori infections,  Bioorganic & Medicinal Chemistry , 2018, 26(14): 4145-4152.

发明专利：

[1] 朱海亮、任深圳、朱丹、王忠长、徐琛：一类含NO供体的二茂铁-吡唑磺胺衍生物的设计、合成及其生物活性评价。申请号：CN201810766827.1，公开号：CN110698519A.

[2] 朱海亮、任深圳、朱晓华、王忠长、赵劲：一类含吡唑骨架的白杨素衍生物的设计、合成及其生物活性评价，申请号：CN201810766829.0，公开号：CN110698464A.

【联系方式】

邮箱：rensz@hebut.edu.cn